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May one hold on to a Mezuzah as a Segulah for protection?<a href="#ftn1" name="ftnref1">[1]</a>
Yes. The Rebbe Rayatz was accustomed to have a Mezuzah on his desk.<a href="#ftn2" name="ftnref2">[2]</a> 
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May one give a Mezuzah to a gentile as a Segulah for protection?<a href="#ftn3" name="ftnref3">[3]</a>
Yes. 
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<a href="#ftnref1" name="ftn1">[1]</a> Yerushalmi Peah 1/1; Tosefes Yom Tov on Keilim 17/15; Likkutei Sichos 19/121, Igros Kodesh 4/159; printed in Shulchan Menachem 234-236
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<a href="#ftnref2" name="ftn2">[2]</a> Rebbe ibid
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<a href="#ftnref3" name="ftn3">[3]</a> Yerushalmi Peah 1/1; Likkutei Sichos 19/121, printed in Shulchan Menachem 234-236
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Shulchan Aruch HaRav | Holding a Mezuzah as Segula

May one hold on to a Mezuzah as a Segulah for protection?[1] Yes. The Rebbe Rayatz was accustomed to have a Mezuzah on his desk.[2] May one give a Mezuzah to a gentile as a Segulah for protection?[3] Yes. [1] Yerushalmi Peah 1/1; Tosefes Yom Tov on Keilim 17/15